Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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GLB Brain Sun Cluster Number 18 (241 genes) This page contains all miRNA mediated regulation and functional enrichment for GLB Brain Sun cluster number 18. Information about brain cancer can be found on Wikipedia, and further information about the "GLB Brain Sun" dataset can be found in Sun et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-655 hsa-mir-498 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 102 GO:0006350 transcription, DNA-dependent 77 GO:0006351 transcription, DNA-dependent 61 GO:0006355 regulation of transcription, DNA-dependent 53 GO:0008152 metabolic process 146 GO:0009058 biosynthetic process 98 GO:0009059 macromolecule biosynthetic process 89 GO:0009889 regulation of biosynthetic process 77 GO:0010467 gene expression 93 GO:0010468 regulation of gene expression 76 GO:0010556 regulation of macromolecule biosynthetic process 76 GO:0016070 RNA metabolic process 77 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 78 GO:0019222 regulation of metabolic process 93 GO:0031323 regulation of cellular metabolic process 89 GO:0031326 regulation of cellular biosynthetic process 77 GO:0032774 RNA biosynthetic process 61 GO:0034645 cellular macromolecule biosynthetic process 89 GO:0043170 macromolecule metabolic process 121 GO:0044237 cellular metabolic process 135 GO:0044238 primary metabolic process 138 GO:0044249 cellular biosynthetic process 97 GO:0044260 cellular macromolecule metabolic process 117 GO:0045449 regulation of transcription, DNA-dependent 73 GO:0050794 regulation of cellular process 124 GO:0051252 regulation of RNA metabolic process 54 GO:0060255 regulation of macromolecule metabolic process 83 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-498 TargetScan GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 32 102 241 79 0.6015791 hsa-mir-655 PITA GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 13 102 241 30 0.3732067 hsa-mir-498 TargetScan GO:0006350 transcription, DNA-dependent 23 77 241 79 0.694068 hsa-mir-655 PITA GO:0006350 transcription, DNA-dependent 10 77 241 30 0.3451486 hsa-mir-498 TargetScan GO:0006351 transcription, DNA-dependent 20 61 241 79 0.4333868 hsa-mir-655 PITA GO:0006351 transcription, DNA-dependent 8 61 241 30 0.3337902 hsa-mir-498 TargetScan GO:0006355 regulation of transcription, DNA-dependent 18 53 241 79 0.3511871 hsa-mir-655 PITA GO:0006355 regulation of transcription, DNA-dependent 8 53 241 30 0.1831206 hsa-mir-498 TargetScan GO:0008152 metabolic process 47 146 241 79 0.5414673 hsa-mir-655 PITA GO:0008152 metabolic process 19 146 241 30 0.3013234 hsa-mir-498 TargetScan GO:0009058 biosynthetic process 31 98 241 79 0.5680563 hsa-mir-655 PITA GO:0009058 biosynthetic process 14 98 241 30 0.1800289 hsa-mir-498 TargetScan GO:0009059 macromolecule biosynthetic process 28 89 241 79 0.574347 hsa-mir-655 PITA GO:0009059 macromolecule biosynthetic process 12 89 241 30 0.2800394 hsa-mir-498 TargetScan GO:0009889 regulation of biosynthetic process 24 77 241 79 0.5839247 hsa-mir-655 PITA GO:0009889 regulation of biosynthetic process 11 77 241 30 0.209606 hsa-mir-498 TargetScan GO:0010467 gene expression 30 93 241 79 0.4968826 hsa-mir-655 PITA GO:0010467 gene expression 12 93 241 30 0.3522138 hsa-mir-498 TargetScan GO:0010468 regulation of gene expression 23 76 241 79 0.6597376 hsa-mir-655 PITA GO:0010468 regulation of gene expression 11 76 241 30 0.1944868 hsa-mir-498 TargetScan GO:0010556 regulation of macromolecule biosynthetic process 24 76 241 79 0.5460182 hsa-mir-655 PITA GO:0010556 regulation of macromolecule biosynthetic process 11 76 241 30 0.1944868 hsa-mir-498 TargetScan GO:0016070 RNA metabolic process 26 77 241 79 0.3535763 hsa-mir-655 PITA GO:0016070 RNA metabolic process 10 77 241 30 0.3451486 hsa-mir-498 TargetScan GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 24 78 241 79 0.620863 hsa-mir-655 PITA GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 10 78 241 30 0.3648237 hsa-mir-498 TargetScan GO:0019222 regulation of metabolic process 30 93 241 79 0.4968826 hsa-mir-655 PITA GO:0019222 regulation of metabolic process 12 93 241 30 0.3522138 hsa-mir-498 TargetScan GO:0031323 regulation of cellular metabolic process 29 89 241 79 0.4614344 hsa-mir-655 PITA GO:0031323 regulation of cellular metabolic process 12 89 241 30 0.2800394 hsa-mir-498 TargetScan GO:0031326 regulation of cellular biosynthetic process 24 77 241 79 0.5839247 hsa-mir-655 PITA GO:0031326 regulation of cellular biosynthetic process 11 77 241 30 0.209606 hsa-mir-498 TargetScan GO:0032774 RNA biosynthetic process 20 61 241 79 0.4333868 hsa-mir-655 PITA GO:0032774 RNA biosynthetic process 8 61 241 30 0.3337902 hsa-mir-498 TargetScan GO:0034645 cellular macromolecule biosynthetic process 28 89 241 79 0.574347 hsa-mir-655 PITA GO:0034645 cellular macromolecule biosynthetic process 12 89 241 30 0.2800394 hsa-mir-498 TargetScan GO:0043170 macromolecule metabolic process 42 121 241 79 0.2182318 hsa-mir-655 PITA GO:0043170 macromolecule metabolic process 16 121 241 30 0.2877229 hsa-mir-498 TargetScan GO:0044237 cellular metabolic process 45 135 241 79 0.3658583 hsa-mir-655 PITA GO:0044237 cellular metabolic process 19 135 241 30 0.1445019 hsa-mir-498 TargetScan GO:0044238 primary metabolic process 46 138 241 79 0.3638246 hsa-mir-655 PITA GO:0044238 primary metabolic process 18 138 241 30 0.3032731 hsa-mir-498 TargetScan GO:0044249 cellular biosynthetic process 31 97 241 79 0.5318145 hsa-mir-655 PITA GO:0044249 cellular biosynthetic process 14 97 241 30 0.1671148 hsa-mir-498 TargetScan GO:0044260 cellular macromolecule metabolic process 40 117 241 79 0.2777063 hsa-mir-655 PITA GO:0044260 cellular macromolecule metabolic process 16 117 241 30 0.2249576 hsa-mir-498 TargetScan GO:0045449 regulation of transcription, DNA-dependent 22 73 241 79 0.6631196 hsa-mir-655 PITA GO:0045449 regulation of transcription, DNA-dependent 10 73 241 30 0.2700326 hsa-mir-498 TargetScan GO:0050794 regulation of cellular process 39 124 241 79 0.6237227 hsa-mir-655 PITA GO:0050794 regulation of cellular process 16 124 241 30 0.3396081 hsa-mir-498 TargetScan GO:0051252 regulation of RNA metabolic process 18 54 241 79 0.3926625 hsa-mir-655 PITA GO:0051252 regulation of RNA metabolic process 8 54 241 30 0.1998117 hsa-mir-498 TargetScan GO:0060255 regulation of macromolecule metabolic process 26 83 241 79 0.578939 hsa-mir-655 PITA GO:0060255 regulation of macromolecule metabolic process 12 83 241 30 0.1857956

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